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BRAF Protein (B-Raf proto-oncogene, serine/threonine kinase) (Myc-DYKDDDDK Tag)

BRAF Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715107
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle BRAF Proteine anzeigen
    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 1
    Human
    Quelle
    • 7
    • 3
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses BRAF Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human B-Raf proto-oncogene protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
    Andere Bezeichnung
    B-Raf Proto-Oncogene (BRAF Produkte)
    Synonyme
    B-RAF1, BRAF1, NS7, RAFB1, C-RMIL, RMIL, B-Raf, braf1, rafb1, b-raf1, sierrabraf, BRAF, 9930012E13Rik, AA120551, AA387315, AA473386, B-raf, Braf-2, Braf2, C230098H17, C87398, D6Ertd631e, braf, fc48g01, wu:fc48g01, B-Raf proto-oncogene, serine/threonine kinase, B-Raf proto-oncogene, serine/threonine kinase S homeolog, Braf transforming gene, si:dkey-222f8.3, BRAF, Braf, braf.S, braf, si:dkey-222f8.3
    Hintergrund
    This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
    Molekulargewicht
    84 kDa
    NCBI Accession
    NP_004324
    Pathways
    MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie
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