IL-6 Protein (AA 29-212)
Kurzübersicht für IL-6 Protein (AA 29-212) (ABIN2018145)
Target
Alle IL-6 (IL6) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 29-212
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Produktmerkmale
- ED50 < 0.06 ng/mL, measured in a cell proliferation assay using 7TD1 cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 6 (IL6) (AA 30-212) protein (His tag,mFc Tag)
IL6 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ADA, AM, ScA
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 28-212) (Active) protein (His tag)IL6 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 29-212) (Active) proteinIL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Spezies: Human Wirt: HEK-293 Cells > 97 % AcA, CC Active
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 1-212) protein (GST tag)IL6 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, AcA Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Human Interleukin-6 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-6 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Andere Bezeichnung
- Interleukin-6 (IL-6)
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Hintergrund
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Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that acts in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, as well as nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction, to be released to the blood stream to help break down fats and improve insulin resistance.
Synonyms: 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 -
Molekulargewicht
- 21-23 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q75MH2
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Pathways
- TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Target
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