IL-6 Protein (AA 25-211)
Kurzübersicht für IL-6 Protein (AA 25-211) (ABIN2018141)
Target
Alle IL-6 (IL6) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 25-211
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Produktmerkmale
- ED50 < 3 pg/mL, measured by a cell proliferation assay using 7TD1 Cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 6 (IL6) (AA 30-212) protein (mFc-His Tag)
IL6 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 28-212) (Active) protein (His tag)IL6 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 29-212) (Active) proteinIL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Spezies: Human Wirt: HEK-293 Cells > 97 % AcA, CC Active
Interleukin 6 (IL6) (AA 47-241) protein (His tag)IL6 Spezies: Huhn Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 6 (IL6) (AA 21-207) protein (His tag)IL6 Spezies: Hund Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Andere Bezeichnung
- Interleukin-6 (IL-6)
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Hintergrund
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Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
Synonyms: 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 -
Molekulargewicht
- 21-26 kDa , observed by reducing SDS-PAGE.
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UniProt
- P20607
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Pathways
- TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Target
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