IFNB1 Protein (AA 22-187)
Kurzübersicht für IFNB1 Protein (AA 22-187) (ABIN2017995)
Target
Alle IFNB1 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 22-187
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Produktmerkmale
- ED50 < 0.1 ng/mL, measured in a proliferation assay using TF-1 Cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)
IFNB1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)IFNB1 Spezies: Maus Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, beta 1, Fibroblast (IFNB1) (AA 1-187) protein (GST tag)IFNB1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187) protein (Fc Tag)IFNB1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187), (full length) protein (GST tag)IFNB1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Human Interferon-beta remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interferon-beta should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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Andere Bezeichnung
- Interferon-beta
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Hintergrund
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Interferon-beta (IFN-beta), acting via STAT1 and STAT2, is known to upregulate and downregulate a wide variety of genes, most of which are involved in the antiviral immune response. It is a member of Type I IFNs, which include IFN-alpha, -beta, tau, and omega. IFN-beta plays an important role in inducing non-specific resistance against a broad range of viral infections. It also affects cell proliferation and modulates immune responses.
Synonyms: Leukocyte interferon, B cell interferon, Type I interferon -
Molekulargewicht
- 23 kDa, observed by reducing SDS-PAGE.
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UniProt
- P01574
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Pathways
- JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagie, Inflammasome
Target
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