NGFB Protein

Produktnummer ABIN1880418

Dieses Native NGFB-Protein wird in Maus exprimiert.

Kurzübersicht für NGFB Protein (ABIN1880418)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Maus

Quelle: Maus

Reinheit: > 95 % by SDS-PAGE

Produktdetails

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with sterile 18 mΩ/cm^3 H2O.

Buffer: 10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Antigendetails

Target: NGFB (Nerve Growth Factor beta (NGFB))

Andere Bezeichnung: NGF beta

Hintergrund: Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.

Molekulargewicht: 26.5 kDa

Pathways: NF-kappaB Signalweg, RTK Signalweg, Regulation of Cell Size