PKC iota Produkte
(Protein Kinase C, iota (PRKCI))
Kategorien
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008].
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Ausgewählte PKC iota Kategorien
PKC iota Antikörper
High quality antibodies with extensive validation data.
PKC iota ELISA Kits
Reliable ELISA kits for a wide range of species.
PKC iota Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PKC iota Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7444109
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, RNAi
Validierungen
- (5)
Kat. Nr.
ABIN562391
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN391010
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene PKC iota ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1116783
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1116784
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN995121
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PKC iota Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
Kat. Nr.
ABIN1316270
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509106
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
Kat. Nr.
ABIN7504509
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PKC iota Produkten
: "PKCiota promotes ovarian tumor progression through deregulation of cyclin E." in: Oncogene, Vol. 35, Issue 19, pp. 2428-40, (2016) (PubMed).: "PRKCI negatively regulates autophagy via PIK3CA/AKT-MTOR signaling." in: Biochemical and biophysical research communications, Vol. 470, Issue 2, pp. 306-12, (2016) (PubMed).
: "Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 9, pp. G745-56, (2015) (PubMed).
: "Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells." in: Biology open, Vol. 2, Issue 11, pp. 1264-9, (2013) (PubMed).
: "Significance and expression of atypical protein kinase C-iota in human hepatocellular carcinoma." in: The Journal of surgical research, Vol. 154, Issue 1, pp. 143-9, (2009) (PubMed).
: "Correlation of aPKC-iota and E-cadherin expression with invasion and prognosis of cholangiocarcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 1, pp. 70-5, (2008) (PubMed).
: "Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells." in: Journal of cell science, Vol. 121, Issue Pt 5, pp. 644-54, (2008) (PubMed).
: "Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota." in: Cancer research, Vol. 68, Issue 18, pp. 7403-8, (2008) (PubMed).
: "Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms." in: The Journal of biological chemistry, Vol. 281, Issue 44, pp. 33773-88, (2006) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
Synonyme und alternative Namen zu PKC iota
protein kinase C iota (PRKCI), protein kinase C, iota (prkci), protein kinase C, iota (Prkci), protein kinase C iota (Prkci), 2310021H13Rik, AI427505, aPKClambda, aPKC[l], DXS1179E, hal, has, mKIAA4165, nPKC-iota, PKC, PKCI, Pkci, Pkcl, PKClambda, PRKCI, PrkclBezeichner auf Proteinebene für PKC iota
- PRKC-lambda/iota
- aPKC-lambda/iota
- atypical protein kinase C-lambda/iota
- protein kinase C iota type
- heart and soul protein
- nPKC-iota
- protein kinase C, iota
- protein kinase C iota
- protein kinase C, lambda
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