PDE4C Produkte
(phosphodiesterase 4C, CAMP-Specific (PDE4C))
Kategorien
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
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Ausgewählte PDE4C Kategorien
PDE4C Antikörper
High quality antibodies with extensive validation data.
PDE4C Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDE4C Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN518723
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF, IHC, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6259147
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN518724
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PDE4C ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231743
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDE4C Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7557172
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7550651
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7578721
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE4C Produkten
: "siRNA-mediated silencing of phosphodiesterase 4B expression affects the production of cytokines in endotoxin-stimulated primary cultured microglia." in: Experimental and therapeutic medicine, Vol. 12, Issue 4, pp. 2257-2264, (2017) (PubMed).: "Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1914-22, (2016) (PubMed).
: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).
: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).
: "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 4, pp. L441-50, (2011) (PubMed).
: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).
: "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." in: Neurotoxicology and teratology, Vol. 26, Issue 1, pp. 73-81, (2004) (PubMed).
Synonyme und alternative Namen zu PDE4C
phosphodiesterase 4C (PDE4C), phosphodiesterase 4C, cAMP-specific a (pde4ca), phosphodiesterase 4C (pde4c), phosphodiesterase 4C, cAMP specific (Pde4c), phosphodiesterase 4C (Pde4c), dpde1, Dpde1, DPDE1, dunce, E130301F19Rik, im:7160317, pde4c, PDE4C, si:dkey-149i17.5Bezeichner auf Proteinebene für PDE4C
- cAMP-specific 3',5'-cyclic phosphodiesterase 4C
- phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)
- Pde43
- phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog)
- PDE21
- phosphodiesterase E1 dunce homolog
- cAMP-specific 35-cyclic phosphodiesterase 4C
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