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MICB Produkte

(MHC Class I Polypeptide-Related Sequence B (MICB))

Kategorien

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules\; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq, Jul 2008].

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Ausgewählte MICB Kategorien

MICB Antikörper

High quality antibodies with extensive validation data.

MICB ELISA Kits

Reliable ELISA kits for a wide range of species.

MICB Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MICB Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN3042366
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (1)
Kat. Nr. ABIN1108239
Menge 0.2 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation IP
Validierungen
  • (1)
Kat. Nr. ABIN517933
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MICB ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975551
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1672867
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6719775
Menge 1 kit
Datenblatt Datenblatt

Empfohlene MICB Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN6964108
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3083796
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3083795
Menge 0.5 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MICB Produkten

Son, Lee, Koh, Shin, Bae, Yang, Park: "Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells." in: Scientific reports, Vol. 6, pp. 32470, (2016) (PubMed).

Nielsen, Dyring-Andersen, Schmidt, Witherden, Lovato, Woetmann, Ødum, Poulsen, Havran, Geisler, Bonefeld: "NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity." in: The Journal of investigative dermatology, Vol. 135, Issue 5, pp. 1311-9, (2015) (PubMed).

Giannattasio, Weil, Kloess, Ansari, Stelzer, Cerwenka, Steinle, Koehl, Koch: "Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids." in: BMC cancer, Vol. 15, pp. 351, (2015) (PubMed).

Zingoni, Cecere, Vulpis, Fionda, Molfetta, Soriani, Petrucci, Ricciardi, Fuerst, Amendola, Mytilineos, Cerboni, Paolini, Cippitelli, Santoni: "Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 2, pp. 736-48, (2015) (PubMed).

Esteso, Luzón, Sarmiento, Gómez-Caro, Steinle, Murphy, Carbone, Valés-Gómez, Reyburn: "Altered microRNA expression after infection with human cytomegalovirus leads to TIMP3 downregulation and increased shedding of metalloprotease substrates, including MICA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 3, pp. 1344-52, (2014) (PubMed).

Gómez-Lomelí, Bravo-Cuellar, Hernández-Flores, Jave-Suárez, Aguilar-Lemarroy, Lerma-Díaz, Domínguez-Rodríguez, Sánchez-Reyes, Ortiz-Lazareno: "Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor." in: Cancer cell international, Vol. 14, Issue 1, pp. 100, (2014) (PubMed).

Nachmani, Zimmermann, Oiknine Djian, Weisblum, Livneh, Khanh Le, Galun, Horejsi, Isakov, Shomron, Wolf, Hengel, Mandelboim: "MicroRNA editing facilitates immune elimination of HCMV infected cells." in: PLoS pathogens, Vol. 10, Issue 2, pp. e1003963, (2014) (PubMed).

Fielding, Aicheler, Stanton, Wang, Han, Seirafian, Davies, McSharry, Weekes, Antrobus, Prodhomme, Blanchet, Sugrue, Cuff, Roberts, Davison, Lehner, Wilkinson, Tomasec: "Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation." in: PLoS pathogens, Vol. 10, Issue 5, pp. e1004058, (2014) (PubMed).

Leung, Vong, Lin, Janke, Chen, Leung: "Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXR? activation." in: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2675-92, (2013) (PubMed).

Madrid, Ganem: "Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44." in: Journal of virology, Vol. 86, Issue 16, pp. 8693-704, (2012) (PubMed).

Synonyme und alternative Namen zu MICB

MHC class I polypeptide-related sequence B (MICB), MHC class I-related protein-like (LOC512825), PERB11.2

Bezeichner auf Proteinebene für MICB

  • MHC class I chain-related protein B
  • MHC class I mic-B antigen
  • MHC class I-like molecule PERB11.2-IMX
  • MIC-B
  • stress inducible class I homolog
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