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MICA Produkte

(MHC Class I Polypeptide-Related Sequence A (MICA))

Kategorien

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].

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Ausgewählte MICA Kategorien

MICA Antikörper

High quality antibodies with extensive validation data.

MICA ELISA Kits

Reliable ELISA kits for a wide range of species.

MICA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MICA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, IF, IHC (p)
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN652566
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IP
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN94329
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Cat, Cow, Human, Non-Human Primate
Applikation ELISA, FACS, IP, ICC, IHC (fro), CyTOF
Validierungen
  • (9)
  • (3)
Kat. Nr. ABIN2749085
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene MICA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968602
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN411398
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6386157
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MICA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275256
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275255
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275254
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MICA Produkten

Srpan, Ambrose, Karampatzakis, Saeed, Cartwright, Guldevall, De Matos, Önfelt, Davis: "Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells." in: The Journal of cell biology, Vol. 217, Issue 9, pp. 3267-3283, (2018) (PubMed).

Chen, Zhidan, Xia, Zhaoxia, Qing, Qiang, Haipeng, Hengxiao: "Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).

Zanetti, Ziblat, Torres, Zwirner, Bouzat: "Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells." in: The Journal of biological chemistry, Vol. 291, Issue 32, pp. 16541-52, (2016) (PubMed).

Tyciakova, Matuskova, Bohovic, Polakova, Toro, Skolekova, Kucerova: "Genetically engineered mesenchymal stromal cells producing TNF? have tumour suppressing effect on human melanoma xenograft." in: The journal of gene medicine, (2015) (PubMed).

Shi, Li, Couturier, Yang, Guo, He, Lewis, Zhou: "Allele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism." in: The open rheumatology journal, Vol. 9, pp. 60-4, (2015) (PubMed).

Taniguchi, Koyano, Suzutani, Goishi, Ito, Morioka, Nakamura, Yamada, Oka, Inoue: "A Thr72Ala polymorphism in the NKG2D gene is associated with early symptomatic congenital cytomegalovirus disease." in: Infection, Vol. 43, Issue 3, pp. 353-9, (2015) (PubMed).

Xiang, Liu, Zheng, Liu, Lv, Gao, Hu, Lam, Chan, Yang, Chen, Tsao, Bonneville, Lau, Tu: "Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease." in: Cancer cell, Vol. 26, Issue 4, pp. 565-76, (2014) (PubMed).

Umebayashi, Kiyota, Koya, Tanaka, Onishi, Katano, Morisaki: "An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro." in: Anticancer research, Vol. 34, Issue 8, pp. 4509-19, (2014) (PubMed).

Morisaki, Hirano, Koya, Kiyota, Tanaka, Umebayashi, Onishi, Katano: "NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors." in: Anticancer research, Vol. 34, Issue 8, pp. 4529-38, (2014) (PubMed).

Gómez-Lomelí, Bravo-Cuellar, Hernández-Flores, Jave-Suárez, Aguilar-Lemarroy, Lerma-Díaz, Domínguez-Rodríguez, Sánchez-Reyes, Ortiz-Lazareno: "Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor." in: Cancer cell international, Vol. 14, Issue 1, pp. 100, (2014) (PubMed).

Synonyme und alternative Namen zu MICA

MHC class I polypeptide-related sequence A (MICA), MIC-A, PERB11.1

Bezeichner auf Proteinebene für MICA

  • HLA class I antigen
  • MHC class I chain-related protein A
  • stress inducible class I homolog
  • F10 alpha chain-like
  • class I histocompatibility antigen
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