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Metabotropic Glutamate Receptor 5 Antikörper

(Glutamate Receptor, Metabotropic 5 (GRM5))
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009].

Häufig verwendete Metabotropic Glutamate Receptor 5 Antikörper

Aktuelle Publikationen für unsere Metabotropic Glutamate Receptor 5 Antikörper

Lee, Vyas, Garner, Montgomery: "Autism-associated Shank3 mutations alter mGluR expression and mGluR-dependent but not NMDA receptor-dependent long-term depression." in: Synapse (New York, N.Y.), Vol. 73, Issue 8, pp. e22097, (2019) (PubMed).

Cheyne, Grant, Butler-Munro, Foote, Connor, Montgomery: "Synaptic integration of newly generated neurons in rat dissociated hippocampal cultures." in: Molecular and cellular neurosciences, Vol. 47, Issue 3, pp. 203-14, (2011) (PubMed).

Spanagel, Pendyala, Abarca, Zghoul, Sanchis-Segura, Magnone, Lascorz, Depner, Holzberg, Soyka, Schreiber, Matsuda, Lathrop, Schumann, Albrecht: "The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption." in: Nature medicine, Vol. 11, Issue 1, pp. 35-42, (2005) (PubMed).

Pacheco, Ciruela, Casadó, Mallol, Gallart, Lluis, Franco: "Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation." in: The Journal of biological chemistry, Vol. 279, Issue 32, pp. 33352-8, (2004) (PubMed).

Uchino, Sakai, Kashiwagi, Shirai, Shinohara, Hirose, Iino, Yamamura, Saito: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).

Anneser, Ince, Shaw, Borasio: "Differential expression of mGluR5 in human lumbosacral motoneurons." in: Neuroreport, Vol. 15, Issue 2, pp. 271-3, (2004) (PubMed).

Aliase für Metabotropic Glutamate Receptor 5 Antikörper

glutamate receptor, metabotropic 5 (GRM5) Antikörper
glutamate metabotropic receptor 5 (GRM5) Antikörper
glutamate metabotropic receptor 5 (Grm5) Antikörper
glutamate receptor, metabotropic 5 (Grm5) Antikörper
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