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Metabotropic Glutamate Receptor 5 Antikörper (AA 824-1203) (APC)

GRM5 Reaktivität: Ratte WB, IHC, IF, IP, ICC Wirt: Maus Monoclonal S75-33 APC
Produktnummer ABIN2483980
  • Target Alle Metabotropic Glutamate Receptor 5 (GRM5) Antikörper anzeigen
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Bindungsspezifität
    • 40
    • 33
    • 16
    • 15
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 824-1203
    Reaktivität
    • 111
    • 87
    • 83
    • 11
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Ratte
    Wirt
    • 92
    • 45
    • 2
    • 2
    • 1
    Maus
    Klonalität
    • 88
    • 54
    Monoklonal
    Konjugat
    • 45
    • 10
    • 9
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Metabotropic Glutamate Receptor 5 Antikörper ist konjugiert mit APC
    Applikation
    • 120
    • 57
    • 40
    • 35
    • 31
    • 28
    • 19
    • 19
    • 13
    • 13
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Spezifität
    Detects ~130 kDa (both mGluR1 and mGluR5).
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
    Klon
    S75-33
    Isotyp
    IgG1
    Top Product
    Discover our top product GRM5 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN2483980 was sufficient for detection of mGluR1/5 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
    Andere Bezeichnung
    mGluR5 (GRM5 Produkte)
    Synonyme
    GPRC1E antikoerper, MGLUR5 antikoerper, mGlu5 antikoerper, mGluR5 antikoerper, mGlur5 antikoerper, 6430542K11Rik antikoerper, AI850523 antikoerper, Glu5R antikoerper, Gprc1e antikoerper, mGluR5b antikoerper, glutamate receptor, metabotropic 5 antikoerper, glutamate metabotropic receptor 5 antikoerper, GRM5 antikoerper, Grm5 antikoerper
    Hintergrund
    The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers (1,2).
    Gen-ID
    24418
    NCBI Accession
    NP_058708
    UniProt
    P31424
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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