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KIR3DS1 Produkte

(Killer Cell Immunoglobulin-Like Receptor, three Domains, Short Cytoplasmic Tail, 1 (KIR3DS1))

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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

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Empfohlene KIR3DS1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN6142892
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC
Validierungen
  • (2)
Kat. Nr. ABIN7264954
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, ELISA, WB
Validierungen
  • (2)
Kat. Nr. ABIN2488814
Menge 400 μL
Datenblatt Datenblatt

Empfohlene KIR3DS1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3082505
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3082504
Menge 0.5 mg
Datenblatt Datenblatt

Synonyme und alternative Namen zu KIR3DS1

killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 (KIR3DS1), killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 (KIR3DS1), CD158E2, KIR-123FM, KIR-G1, NKAT10

Bezeichner auf Proteinebene für KIR3DS1

  • MHC class I NK cell receptor
  • NKAT-10
  • killer Ig receptor
  • killer cell immunoglobulin-like receptor 3DS1
  • killer cell immunoglobulin-like receptor KIR3DS1
  • natural killer-associated transcript 10
  • killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
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