KIR2DS3 Produkte
(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 3 (KIR2DS3))
Kategorien
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Ausgewählte KIR2DS3 Kategorien
KIR2DS3 Antikörper
High quality antibodies with extensive validation data.
KIR2DS3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KIR2DS3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN651950
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF
Validierungen
- (1)
Kat. Nr.
ABIN7157515
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN517338
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene KIR2DS3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3082503
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3099945
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2724259
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KIR2DS3 Produkten
: "Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule." in: Genes and immunity, Vol. 10, Issue 2, pp. 162-73, (2009) (PubMed).Synonyme und alternative Namen zu KIR2DS3
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3 (KIR2DS3), NKAT7Bezeichner auf Proteinebene für KIR2DS3
- MHC class I NK cell receptor
- NKAT-7
- killer cell immunoglobulin-like receptor 2DS3
- natural killer cell inhibitory receptor
- natural killer-associated transcript 7
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