KIR3DL2 Produkte
(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 (KIR3DL2))
Kategorien
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011].
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Ausgewählte KIR3DL2 Kategorien
KIR3DL2 Antikörper
High quality antibodies with extensive validation data.
KIR3DL2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KIR3DL2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7189471
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC
Validierungen
- (2)
Kat. Nr.
ABIN2856893
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF
Validierungen
- (1)
Kat. Nr.
ABIN7157528
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene KIR3DL2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275102
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Rhesus Monkey
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275101
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3082703
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KIR3DL2 Produkten
: "Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1146-1158, (2018) (PubMed).: "α3-Deletion Isoform of HLA-A11 Modulates Cytotoxicity of NK Cells: Correlations with HIV-1 Infection of Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 6, pp. 2030-2042, (2017) (PubMed).
: "The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events." in: PLoS pathogens, Vol. 11, Issue 12, pp. e1005286, (2015) (PubMed).
: "Contenders in FasL/TNF death signaling." in: Cell, Vol. 81, Issue 4, pp. 479-82, (1995) (PubMed).
Synonyme und alternative Namen zu KIR3DL2
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 (KIR3DL2), CD158K, NKAT-4, NKAT4, NKAT4B, p140Bezeichner auf Proteinebene für KIR3DL2
- CD158 antigen-like family member K
- KIR antigen 3DL2
- MHC class I NK cell receptor
- killer Ig receptor
- killer cell immunoglobulin-like receptor 3DL2
- killer cell immunoglobulin-like receptor KIR3DL2
- natural killer cell inhibitory receptor
- natural killer-associated transcript 4
- p70 NK receptor CL-5
- p70 killer cell inhibitory receptor
- p70 natural killer cell receptor clone CL-5
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