KIR2DL1 Produkte
(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
Kategorien
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Ausgewählte KIR2DL1 Kategorien
KIR2DL1 Antikörper
High quality antibodies with extensive validation data.
KIR2DL1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KIR2DL1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7157495
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP
Validierungen
- (2)
Kat. Nr.
ABIN165422
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, ICC, IF
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN532938
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene KIR2DL1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730430
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene KIR2DL1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275084
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275085
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308691
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KIR2DL1 Produkten
: "Eomesodermin and T-bet mark developmentally distinct human natural killer cells." in: JCI insight, Vol. 2, Issue 5, pp. e90063, (2017) (PubMed).: "NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2762-71, (2016) (PubMed).
: "New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells." in: Journal of leukocyte biology, Vol. 100, Issue 3, pp. 471-9, (2016) (PubMed).
: "Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 9, pp. 4524-36, (2015) (PubMed).
: "The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3262-72, (2015) (PubMed).
: "2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells." in: Genes and immunity, Vol. 16, Issue 5, pp. 301-10, (2015) (PubMed).
: "Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles." in: Journal of immunology research, Vol. 2015, pp. 754373, (2015) (PubMed).
: "Tissue-Specific Education of Decidual NK Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3026-32, (2015) (PubMed).
: "Coordinated expression of DNAM-1 and LFA-1 in educated NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4518-27, (2015) (PubMed).
: "Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 6, pp. 2467-71, (2015) (PubMed).
Synonyme und alternative Namen zu KIR2DL1
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1), killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR2DL1), CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1Bezeichner auf Proteinebene für KIR2DL1
- CD158 antigen-like family member A
- MHC class I NK cell receptor
- NKAT-1
- killer Ig receptor
- killer cell immunoglobulin-like receptor 2DL1
- killer inhibitory receptor 2-2-1
- natural killer-associated transcript 1
- p58 NK cell inhibitory receptor NKR-K6
- p58 NK receptor CL-42/47.11
- p58 killer cell inhibitory receptor KIR-K64
- p58 natural killer cell receptor clones CL-42/47.11
- p58.1 MHC class-I-specific NK receptor
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