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KLC1 Produkte

(Kinesin Light Chain 1 (KLC1))

Kategorien

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos\; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008].

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Ausgewählte KLC1 Kategorien

KLC1 Antikörper

High quality antibodies with extensive validation data.

KLC1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KLC1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7434992
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN652577
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN2854634
Menge 100 μL
Datenblatt Datenblatt

Empfohlene KLC1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957313
Menge 96 tests
Datenblatt Datenblatt

Empfohlene KLC1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3082565
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3132110
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7396514
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KLC1 Produkten

Holt, Fuller, Lam, Sewry, Shirran, Zhang, Shanahan, Morris: "Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle." in: Scientific reports, Vol. 9, Issue 1, pp. 14202, (2019) (PubMed).

Carpentier, Gao, Ewles, Morgan, Smith: "Vaccinia virus protein complex F12/E2 interacts with kinesin light chain isoform 2 to engage the kinesin-1 motor complex." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004723, (2015) (PubMed).

Chu, Morfini, Langhamer, He, Brady, Kordower: "Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease." in: Brain : a journal of neurology, Vol. 135, Issue Pt 7, pp. 2058-73, (2012) (PubMed).

Synonyme und alternative Namen zu KLC1

kinesin family member 2A (KIF2A), kinesin light chain 1 (KLC1), kinesin light chain 1 (Klc1), kinesin light chain 1b (klc1b), kinesin light chain 1a (klc1a), kinesin light chain 1 (klc1), kinesin light chain 1 L homeolog (klc1.L), AI874768, HK2, KIF2, kinesin-II, KLC, klc, klc1, Klc2, KNS2, Kns2, kns2, KNS2A, kns2a, wu:fj17e04, zgc:55666, zgc:66299, zgc:77660

Bezeichner auf Proteinebene für KLC1

  • Kinesin, heavy chain, 2
  • kinesin-2
  • kinesin-like protein KIF2A
  • KLC 1
  • kinesin 2 60/70kDa
  • medulloblastoma antigen MU-MB-2.50
  • kinesin 2
  • kinesin light chain 1
  • kinesin light chain 2
  • kinesin light chain 4
  • kinesin ii
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