FDPS Produkte
(Farnesyl Diphosphate Synthase (FDPS))
Kategorien
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008].
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Ausgewählte FDPS Kategorien
FDPS Antikörper
High quality antibodies with extensive validation data.
FDPS ELISA Kits
Reliable ELISA kits for a wide range of species.
FDPS Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FDPS Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), ICC, IF
Validierungen
- (5)
Kat. Nr.
ABIN2856081
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IP
Validierungen
- (4)
Kat. Nr.
ABIN7152571
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), IF
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN1882080
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene FDPS ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6955697
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955696
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951338
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FDPS Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353934
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353936
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3080231
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FDPS Produkten
: "Nebulized Heparin Attenuates Pulmonary Coagulopathy and Inflammation through Alveolar Macrophages in a Rat Model of Acute Lung Injury." in: Thrombosis and haemostasis, Vol. 117, Issue 11, pp. 2125-2134, (2018) (PubMed).: "Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells." in: BMC cancer, Vol. 15, pp. 4, (2015) (PubMed).
: "Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?" in: World journal of urology, Vol. 31, Issue 2, pp. 345-50, (2013) (PubMed).
: "Antithrombin III injection via the portal vein suppresses liver damage." in: World journal of gastroenterology, Vol. 18, Issue 16, pp. 1884-91, (2012) (PubMed).
: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
: "Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells." in: The Biochemical journal, Vol. 429, Issue 2, pp. 347-57, (2010) (PubMed).
: "Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells." in: Biochemical pharmacology, Vol. 79, Issue 5, pp. 777-83, (2010) (PubMed).
: "Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 8118-24, (2009) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ..." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4607-14, (1990) (PubMed).
Synonyme und alternative Namen zu FDPS
Farnesyl pyrophosphate synthase (Fpps), farnesyl diphosphate synthase (fdps), farnesyl diphosphate synthase L homeolog (fdps.L), farnesyl pyrophosphate synthase (MGG_08649), farnesyl pyrophosphate synthetase (TP03_0857), farnesyl pyrophosphate synthetase (Tb09.160.4300), farnesyl-pyrophosphate synthetase (fpp), farnesyl pyrophosphate synthetase (BBOV_I000120), FDP synthase (fps), Farnesyl pyrophosphate synthetase (fpps), farnesyl diphosphate synthase (FDPS), farnesyl diphosphate synthase (Fdps), farnesyl diphosphate synthetase (Fdps), farnesyl pyrophosphate synthase 1 (fps1), (2E, 16.m00760, 6030492I17Rik, Ac2-125, AI256750, CG12389, DDBDRAFT_0206220, DDBDRAFT_0215017, DDB_0206220, DDB_0215017, Dmel\\CG12389, DmFPPS, DmFPPSase, DmFPS, Fdpsl1, fpps, FPPS, FPS, fps, l(2)k06103, mKIAA1293, NCU01175.1, v(2)k03514Bezeichner auf Proteinebene für FDPS
- farnesyl pyrophosphate synthase
- CG12389-PA
- Fpps-PA
- farnesyl diphosphate synthase
- farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
- farnesyl pyrophosphate synthetase
- Farnesyl pyrophosphate synthetase
- (2E,6E)-farnesyl diphosphate synthase
- FPP synthase
- FPP synthetase
- dimethylallyltranstransferase
- farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase
- geranyltranstransferase
- CR 39
- cholesterol-regulated 39 kDa protein
- farnesyl diphosphate synthetase
- testis-specific farnesyl pyrophosphate synthetase
- FPS
- 6E)-farnesyl diphosphate synthase
- FPPS
- GRMZM2G168681
- PCO074380
- PCO074380(592)
- PCO074380_ov
- PCO074380b
- QBB18h08
- geranylgeranyl-diphosphate synthase
- gnp_QBB18h08b
- gpm430b
- prenyltransferase
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