FDPS Antikörper (N-Term)

Produktnummer ABIN1882080

Produktdetails anti-FDPS Antikörper

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Bindungsspezifität: AA 82-112, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FDPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FDPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-112 amino acids from the N-terminal region of human FDPS.

Klon: RB4783-4784

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:100. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-FDPS Antikörper (ABIN1882080)

Wilkin, Kutsunai, Edwards et al.: "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ..." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4607-14, (1990) (PubMed).

Sheares, White, Molowa, Chan, Ding, Kroon, Bostedor, Karkas: "Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells." in: Biochemistry, Vol. 28, Issue 20, pp. 8129-35, (1990) (PubMed).

Details zu FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Andere Bezeichnung: FDPS (FDPS Produkte)

Synonyme: CG12389 antikoerper, DmFPPS antikoerper, DmFPPSase antikoerper, DmFPS antikoerper, Dmel\\CG12389 antikoerper, FPS antikoerper, fpps antikoerper, fps antikoerper, l(2)k06103 antikoerper, v(2)k03514 antikoerper, NCU01175.1 antikoerper, 16.m00760 antikoerper, DDBDRAFT_0206220 antikoerper, DDBDRAFT_0215017 antikoerper, DDB_0206220 antikoerper, DDB_0215017 antikoerper, FPPS antikoerper, Ac2-125 antikoerper, (2E antikoerper, 6030492I17Rik antikoerper, AI256750 antikoerper, Fdpsl1 antikoerper, mKIAA1293 antikoerper, Farnesyl pyrophosphate synthase antikoerper, farnesyl diphosphate synthase antikoerper, farnesyl diphosphate synthase L homeolog antikoerper, farnesyl pyrophosphate synthase antikoerper, farnesyl pyrophosphate synthetase antikoerper, farnesyl-pyrophosphate synthetase antikoerper, FDP synthase antikoerper, Farnesyl pyrophosphate synthetase antikoerper, farnesyl diphosphate synthetase antikoerper, farnesyl pyrophosphate synthase 1 antikoerper, Fpps antikoerper, fdps antikoerper, fdps.L antikoerper, MGG_08649 antikoerper, TP03_0857 antikoerper, Tb09.160.4300 antikoerper, fpp antikoerper, BBOV_I000120 antikoerper, fps antikoerper, fpps antikoerper, FDPS antikoerper, Fdps antikoerper, fps1 antikoerper

Hintergrund: The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.

Molekulargewicht: 48275

NCBI Accession: NP_001129293, NP_001129294, NP_001229753, NP_001229754, NP_001995

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation