FCAR Produkte
(Fc Fragment of IgA, Receptor For (FCAR))
Kategorien
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte FCAR Kategorien
FCAR Antikörper
High quality antibodies with extensive validation data.
FCAR ELISA Kits
Reliable ELISA kits for a wide range of species.
FCAR Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FCAR Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN5684138
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7443131
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Non-Human Primate
Applikation
FACS
Validierungen
- (2)
Kat. Nr.
ABIN4888509
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene FCAR ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6955737
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882811
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN991686
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FCAR Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274249
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Human Cells
Validierungen
Kat. Nr.
ABIN1096636
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7576007
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FCAR Produkten
: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).: "Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis." in: BBA clinical, Vol. 5, pp. 79-84, (2016) (PubMed).
: "Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered Fc?R Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137474, (2015) (PubMed).
: "Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 12, pp. 4974-9, (2011) (PubMed).
: "Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 953-60, (2010) (PubMed).
: "Intracellular pools of FcalphaR (CD89) in human neutrophils are localized in tertiary granules and secretory vesicles, and two FcalphaR isoforms are found in tertiary granules." in: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 551-8, (2007) (PubMed).
: "Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a." in: Clinical and experimental immunology, Vol. 121, Issue 1, pp. 106-11, (2000) (PubMed).
Synonyme und alternative Namen zu FCAR
Fc fragment of IgA receptor (FCAR), Fc fragment of IgA, receptor for (FCAR), CD89Bezeichner auf Proteinebene für FCAR
- IgA Fc receptor
- immunoglobulin A Fc receptor
- immunoglobulin alpha Fc receptor
- Fc fragment of IgA, receptor for, isoform 7
- Fc alpha receptor
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