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Cyclin A Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin A in WB, IHC, ELISA und IP. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
Rockland
Produktnummer ABIN97945
Hersteller Produkt- Nr.: 100-401-151

Kurzübersicht für Cyclin A Antikörper (ABIN97945)

Target

Alle Cyclin A (CCNA2) Antikörper anzeigen
Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reaktivität

  • 87
  • 55
  • 34
  • 29
  • 14
  • 14
  • 12
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 59
  • 34
  • 1
Kaninchen

Klonalität

  • 47
  • 47
Polyklonal

Konjugat

  • 68
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cyclin A Antikörper ist unkonjugiert

Applikation

  • 59
  • 31
  • 23
  • 21
  • 20
  • 16
  • 15
  • 11
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • Hersteller Produkt- Nr.

    100-401-151

    Hersteller

    Rockland

    Verwendungszweck

    Cyclin A Antibody

    Kreuzreaktivität (Details)

    Antiserum will specifically react with a 60 kDa Cyclin A protein from human, rat and mouse tissue.

    Produktmerkmale

    Synonyms: rabbit anti-Cyclin A antibody, CCN1 antibody, CCNA antibody, CCNA2 antibody, Cyclin A2 antibody

    Aufreinigung

    Anti-Cyclin A was prepared from monospecific antiserum by delipidation and defibrination.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: Anti-Cyclin-A Antibody was produced by repeated immunizations with a recombinant protein corresponding to the human cyclin A.

    Immunogen Type: Conjugated Peptide

  • Applikationshinweise

    Immunohistochemistry Dilution: 1:100

    Application Note: Anti-Cyclin-A antibody has been tested by western blot and immunohistochemistry and is suitable for the detection by immunoblot, ELISA, IHC, and IP of human, rat and mouse Cyclin A.  Researchers should determine optimal titers for applications that are not stated below.

    Western Blot Dilution: 1:500 - 1:5,000

    Immunoprecipitation Dilution: 1:100

    ELISA Dilution: 1:5,000 - 1:20,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    80 mg/mL

    Buffer

    Buffer: None

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Rizzolio, Lucchetti, Caligiuri, Marchesi, Caputo, Klein-Szanto, Bagella, Castronovo, Giordano: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).

  • Target

    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

    Andere Bezeichnung

    CCNA2

    Hintergrund

    Background: Anti-Cyclin A detects Cyclin A. Cyclin A is a member of the cyclin family. Cyclin A binds to S phase Cdk2 and is required for the cell to progress through the S phase. Cyclin A/ Cdk2 is inhibited by the complex p21CIP. Anti-Cyclin A Antibody is ideal for investigators involved in Cell Signaling, cell biology and Signal Transduction research.

    Gen-ID

    890

    NCBI Accession

    NP_001228

    UniProt

    P20248

    Pathways

    PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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