Cyclin A Antikörper (N-Term)

Produktnummer ABIN391454

Produktdetails anti-Cyclin A Antikörper

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Bindungsspezifität: AA 51-84, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Cyclin A (CCNA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-84 amino acids from the N-terminal region of human Cyclin A (CCNA2).

Klon: RB14617

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Cyclin A Antikörper (ABIN391454)

Chang, Nam, Kook, Kim, Liu, Yao, Jung, Lemos, Seo, Park, Gim, Hong, Huh, Kim, Tan, Liu, Powis, Park, Liang, Kim: "HNF4? is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer." in: Gut, (2014) (PubMed).

Details zu Cyclin A

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Andere Bezeichnung: Cyclin A (CCNA2) (CCNA2 Produkte)

Synonyme: CCN1 antikoerper, CCNA antikoerper, AA408589 antikoerper, Ccn-1 antikoerper, Ccn1 antikoerper, Ccna antikoerper, CycA2 antikoerper, Cyca antikoerper, cb671 antikoerper, chunp6924 antikoerper, wu:fi36f03 antikoerper, CYCA antikoerper, Cyclin-A2 antikoerper, ccna2 antikoerper, ccn1 antikoerper, ccna antikoerper, ccna1 antikoerper, Cyclin-A antikoerper, cyclinA antikoerper, cyclin A2 antikoerper, cyclin A2 S homeolog antikoerper, cyclin A2 L homeolog antikoerper, CCNA2 antikoerper, Ccna2 antikoerper, ccna2 antikoerper, ccna2.S antikoerper, ccna2.L antikoerper

Hintergrund: CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Molekulargewicht: 48551

Gen-ID: 890

NCBI Accession: NP_001228

UniProt: P20248

Pathways: PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA