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CD11b Antikörper

Name: CD11b Antikörper
SKU: ABIN967477
Price: 350.17 EUR
Availability: InStock

ITGAM Reaktivität: Ratte FACS, IP, WB, IHC (fro), BR Wirt: Maus Monoclonal WT-5 unconjugated

(2 Referenzen)

Produktnummer ABIN967477

Datenblatt (PDF)

Target Alle CD11b (ITGAM) Antikörper anzeigen

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Reaktivität
274

177

73

34

20

19

17

14

11

10

7

4

4

2

2

1
Ratte
Wirt
156

116

105

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
283

94

2
Monoklonal
Konjugat
124

39

33

29

21

10

8

8

7

7

6

6

5

5

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD11b Antikörper ist unkonjugiert
Applikation
284

86

86

81

64

48

38

24

23

21

14

14

11

6

5

5

5

4

4

3

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Marke

BD Pharmingen™

Produktmerkmale

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Aufreinigung

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen

Rat neutrophils

Klon

WT-5

Isotyp

IgA kappa

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Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5 mg/mL

Buffer

Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store undiluted at 4° C.
Watanabe, Arakawa, Fukuda, Higuchi, Kobayashi: "Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta." in: The American journal of pathology, Vol. 150, Issue 3, pp. 971-9, (1997) (PubMed).

Tamatani, Kitamura, Kuida, Shirao, Mochizuki, Suematsu, Schmid-Schönbein, Watanabe, Tsurufuji, Miyasaka: "Characterization of rat LECAM-1 (L-selectin) by the use of monoclonal antibodies and evidence for the presence of soluble LECAM-1 in rat sera." in: European journal of immunology, Vol. 23, Issue 9, pp. 2181-8, (1993) (PubMed).
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung

CD11b (ITGAM Produkte)

Hintergrund

The WT.5 antibody reacts with the alpha subunit of Mac-1 (alphaMbeta2, CD11b/CD18) found on neutrophils and myeloid cells, but not on lymphocytes. Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi. Neutrophil binding to ICAM-1 is blocked by mAb WT.5. This antibody is routinely tested by flow cytometric analysis.
Synonyms: Integrin alphaM chain, Mac-1 alpha chain

Pathways

Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation