CD11b Antikörper (AA 520-570)

Produktnummer ABIN741285

Produktdetails anti-CD11b Antikörper

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Bindungsspezifität: AA 520-570

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD11c

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Referenzen für anti-CD11b Antikörper (ABIN741285)

Ju, Xing, Yang, Zheng, Jia, Zhang, Ren: "An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model." in: BMC immunology, Vol. 17, Issue 1, pp. 31, (2016) (PubMed).

Zhang, Wu, Hayashi, Okada, Nakanishi: "Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 8, pp. 3013-22, (2014) (PubMed).

Di Filippo, Rossi, Ferraro, Maisto, De Angelis, Ferraraccio, Rotondo, DAmico: "Involvement of proteasome and macrophages M2 in the protection afforded by telmisartan against the acute myocardial infarction in Zucker diabetic fatty rats with metabolic syndrome." in: Mediators of inflammation, Vol. 2014, pp. 972761, (2014) (PubMed).

Ahn, Ruiz, Barber: "Intrinsic self-DNA triggers inflammatory disease dependent on STING." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 9, pp. 4634-42, (2014) (PubMed).

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: Cd11b/C (ITGAM Produkte)

Synonyme: CD11b/CD18 antikoerper, CR3 antikoerper, CR3A antikoerper, Cd11b antikoerper, F730045J24Rik antikoerper, Ly-40 antikoerper, MAC1 antikoerper, Mac-1 antikoerper, Mac-1a antikoerper, CD11B antikoerper, MAC-1 antikoerper, MAC1A antikoerper, MO1A antikoerper, SLEB6 antikoerper, C3bi antikoerper, integrin subunit alpha M antikoerper, integrin alpha M antikoerper, integrin, alpha M (complement component 3 receptor 3 subunit) antikoerper, integrin alpha-M antikoerper, ITGAM antikoerper, Itgam antikoerper, LOC100351865 antikoerper

Hintergrund:

Synonyms: CD11C, SLEB6, Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p15,95 alpha chain, Leukocyte adhesion receptor p15,95, ITGAX

Background: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Gen-ID: 3687

UniProt: P20702

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation