CD11b Antikörper (N-Term)
Kurzübersicht für CD11b Antikörper (N-Term) (ABIN654625)
Target
Alle CD11b (ITGAM) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 253-282, N-Term
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This CD11b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human CD11b.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000. WB: 1:1000. WB: 1:500. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart." in: Journal of the American Heart Association, Vol. 2, Issue 5, pp. e000343, (2013) (PubMed).
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Andere Bezeichnung
- CD11b
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Hintergrund
- CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
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Molekulargewicht
- 127179
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Gen-ID
- 3684
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NCBI Accession
- NP_000623, NP_001139280
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UniProt
- P11215
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Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Target
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