VAV1 Antikörper

Produktnummer ABIN967242

Produktdetails anti-VAV1 Antikörper

Target: VAV1 (Vav 1 Oncogene (VAV1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAV1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: Vav (Ab-174) antibody detects endogenous levels of total Vav protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Vav around the phosphorylation site of tyrosine 174 (E-I-YP-E-D).

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-VAV1 Antikörper (ABIN967242)

Amarasinghe, Rosen: "Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain." in: Biochemistry, Vol. 44, Issue 46, pp. 15257-68, (2005) (PubMed).

Charvet, Canonigo, Billadeau, Altman: "Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15289-99, (2005) (PubMed).

Miura-Shimura, Duan, Rao, Reddi, Shimura, Rottapel, Druker, Tsygankov, Band, Band: "Cbl-mediated ubiquitinylation and negative regulation of Vav." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38495-504, (2003) (PubMed).

Kuhne, Ku, Weiss: "A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation." in: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2185-90, (2000) (PubMed).

Details zu VAV1

Target: VAV1 (Vav 1 Oncogene (VAV1))

Andere Bezeichnung: Vav (VAV1 Produkte)

Synonyme: VAV antikoerper, Vav antikoerper, vav-T antikoerper, vav guanine nucleotide exchange factor 1 antikoerper, vav 1 oncogene antikoerper, vav guanine nucleotide exchange factor 1 L homeolog antikoerper, VAV1 antikoerper, Vav1 antikoerper, vav1.L antikoerper

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, BCR Signaling