CD14 Antikörper
Kurzübersicht für CD14 Antikörper (ABIN965766)
Target
Alle CD14 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).
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Aufreinigung
- Antibodies are purified by protein G affinity chromatography.
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Isotyp
- IgG1
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Applikationshinweise
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IHC: Dilution 1:200-1:400
ELISA: Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.2%BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- CD14
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Andere Bezeichnung
- CD14
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Hintergrund
- CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
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Gen-ID
- 929
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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