BAD Antikörper

Produktnummer ABIN965639

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-BAD Antikörper wird verwendet zum Nachweis von BAD in Proben von Human, Maus und Ratte. Er wurde validiert für IHC.

Kurzübersicht für BAD Antikörper (ABIN965639)

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAD Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-BAD Antikörper

Spezifität: BAD (Ab-112) antibody detects endogenous levels of total BAD protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: This antiserum was produced against synthesized non-phosphopeptide derived from human BAD around the phosphorylation site of serine 112 (H-S-SP-Y-P).

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000
IHC: 1:50~1:100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-BAD Antikörper (ABIN965639)

Zhang, Zhang, Shacter: "Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75." in: Molecular and cellular biology, Vol. 24, Issue 14, pp. 6205-14, (2004) (PubMed).

Rice, Washington, Schleman, Beard, Driggers, Ahnen: "Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells." in: Cancer research, Vol. 63, Issue 3, pp. 616-20, (2003) (PubMed).

Wang, Sun, Paller: "Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 44504-11, (2001) (PubMed).

Details zu BAD

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Andere Bezeichnung: BAD

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events