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TLR4 Antikörper (PE)

TLR4 Reaktivität: Human, Hund FACS Wirt: Maus Monoclonal HTA125 PE
Produktnummer ABIN959964
  • Target Alle TLR4 Antikörper anzeigen
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Reaktivität
    • 181
    • 91
    • 72
    • 37
    • 26
    • 24
    • 23
    • 19
    • 9
    • 2
    • 1
    • 1
    • 1
    Human, Hund
    Wirt
    • 132
    • 72
    • 10
    • 4
    Maus
    Klonalität
    • 136
    • 82
    Monoklonal
    Konjugat
    • 96
    • 20
    • 19
    • 15
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR4 Antikörper ist konjugiert mit PE
    Applikation
    • 153
    • 129
    • 54
    • 50
    • 36
    • 31
    • 27
    • 26
    • 26
    • 24
    • 12
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This has been demonstrated to block activation of monocytes with LPS.
    Aufreinigung
    Protein G purified
    Immunogen
    This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).

    Type of Immunogen: Cells
    Klon
    HTA125
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product TLR4 Primärantikörper
  • Applikationshinweise
    Approved: Flo (1 - 2 μg/10 x106)

    Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    PBS, 0.05 % BSA, 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze! Sensitive to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Protect from light.
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Andere Bezeichnung
    TLR4 (TLR4 Produkte)
    Hintergrund
    Name/Gene ID: TLR4
    Family: Toll-like Receptor

    Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll
    Gen-ID
    7099
    UniProt
    O00206
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
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