TLR4 Antikörper (PE)
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- Target Alle TLR4 Antikörper anzeigen
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Reaktivität
- Human, Hund
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TLR4 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This has been demonstrated to block activation of monocytes with LPS.
- Aufreinigung
- Protein G purified
- Immunogen
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This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).
Type of Immunogen: Cells - Klon
- HTA125
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product TLR4 Primärantikörper
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- Applikationshinweise
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Approved: Flo (1 - 2 μg/10 x106)
Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, 0.05 % BSA, 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze! Sensitive to light.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Protect from light.
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- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Andere Bezeichnung
- TLR4 (TLR4 Produkte)
- Hintergrund
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Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll - Gen-ID
- 7099
- UniProt
- O00206
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
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