ULK1 Antikörper
Kurzübersicht für ULK1 Antikörper (ABIN955448)
Target
Alle ULK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody recognizes Human and Mouse Unc-51-like kinase 1 (ULK1).
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Aufreinigung
- Affinity Chromatography on Proteinn A
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Immunogen
- KLH conjugated synthetic peptide selected from Human Unc-51-like kinase 1 (ULK1) Genename: ULK1
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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Andere Bezeichnung
- Unc-51-Like Kinase 1 (ULK1)
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Hintergrund
- ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).Synonyms: KIAA0722, Serine/threonine-protein kinase ULK1
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Molekulargewicht
- 112601 Da
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Gen-ID
- 8408
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NCBI Accession
- NP_003556
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Pathways
- Regulation of Cell Size, Autophagie
Target
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