ULK1 Antikörper (pSer556)

Produktnummer ABIN1881979

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ULK1 in IF und DB. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für ULK1 Antikörper (pSer556) (ABIN1881979)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Dot Blot (DB)

Klon: RB30585

Produktdetails anti-ULK1 Antikörper

Bindungsspezifität: pSer556

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S556 of human ULK1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:200. DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ULK1 Antikörper (ABIN1881979)

Geng, Kohli, Klocke, Roth: "Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent." in: Neuro-oncology, Vol. 12, Issue 5, pp. 473-81, (2010) (PubMed).

Pontén, Westermark: "Properties of human malignant glioma cells in vitro." in: Medical biology, Vol. 56, Issue 4, pp. 184-93, (1978) (PubMed).

Westermark, Pontén, Hugosson: "Determinants for the establishment of permanent tissue culture lines from human gliomas." in: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 81, Issue 6, pp. 791-805, (1974) (PubMed).

Details zu ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Andere Bezeichnung: ULK1

Hintergrund: Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).

Molekulargewicht: 112631

NCBI Accession: NP_003556

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagie