ULK1 Antikörper (AA 567-577)

Produktnummer ABIN5066137

Produktdetails anti-ULK1 Antikörper

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Bindungsspezifität: AA 567-577

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.,Detects ~100 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Peptide Affinity Purified

Immunogen: Synthetic peptide from the mid-protein of Human ULK1 (aa. 567-577)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN5066137 was sufficient for detection of ULK1 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Andere Bezeichnung: ULK1 (ULK1 Produkte)

Synonyme: ATG1 antikoerper, ATG1A antikoerper, UNC51 antikoerper, Unc51.1 antikoerper, hATG1 antikoerper, si:dkey-11o18.7 antikoerper, ulk1 antikoerper, ULK1 antikoerper, AU041434 antikoerper, mKIAA0722 antikoerper, zgc:195008 antikoerper, unc-51 like autophagy activating kinase 1 antikoerper, unc-51 like kinase 1 antikoerper, unc-51 like autophagy activating kinase 1a antikoerper, ULK1 antikoerper, Ulk1 antikoerper, ulk1b antikoerper, ulk1a antikoerper

Hintergrund: UNC-51 like kinase 1 (ULK1) is widely expresed and contains an amino-terminal kinase domain followed by a central proline-serine rich domain and a highly conserved carboxy-terminal domain. It has been linked to axon growth and is essential for autophagy. Structurally, ULK1 is similar to ATG1, and it appears that both Atg1/ULK1 can bind to several ATG proteins regulating phosphorylation states and protein trafficking.

Gen-ID: 8408

NCBI Accession: NP_003556

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagie