IRAK4 Antikörper (N-Term)
Kurzübersicht für IRAK4 Antikörper (N-Term) (ABIN952943)
Target
Alle IRAK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 32-60, N-Term
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Spezifität
- This antibody recognizes Human IRAK4 (N-term).
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Aufreinigung
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 32-60 amino acids from the N-terminal region of Human IRAK4.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Andere Bezeichnung
- IRAK4
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Hintergrund
- This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64
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Molekulargewicht
- 51530 Da
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Gen-ID
- 51135
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NCBI Accession
- NP_001107654
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Pathways
- NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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