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IL-6 Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-IL-6-Antikörper wurde für WB, FACS, IHC (p) und EIA validiert. Er ist geeignet, IL-6 in Proben von Human zu detektieren.
Produktnummer ABIN952928

Kurzübersicht für IL-6 Antikörper (Middle Region) (ABIN952928)

Target

Alle IL-6 (IL6) Antikörper anzeigen
IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität

  • 219
  • 141
  • 80
  • 44
  • 35
  • 23
  • 21
  • 13
  • 12
  • 10
  • 8
  • 7
  • 5
  • 3
  • 2
Human

Wirt

  • 233
  • 149
  • 69
  • 16
  • 6
  • 5
  • 3
  • 2
Kaninchen

Klonalität

  • 256
  • 222
  • 2
Polyklonal

Konjugat

  • 292
  • 69
  • 30
  • 13
  • 11
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IL-6 Antikörper ist unkonjugiert

Applikation

  • 366
  • 204
  • 144
  • 134
  • 133
  • 62
  • 47
  • 41
  • 41
  • 35
  • 25
  • 24
  • 22
  • 18
  • 15
  • 10
  • 7
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 30
    • 29
    • 28
    • 15
    • 15
    • 15
    • 12
    • 11
    • 9
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-55, Middle Region

    Spezifität

    This antibody recognizes Human Interleukin-6 (Center).

    Aufreinigung

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 26-55 amino acids from the Central region of Human Interleukin-6 Genename: IL6

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    IL-6 (IL6) (Interleukin 6 (IL6))

    Andere Bezeichnung

    Interleukin-6 (IL6)

    Hintergrund

    This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2

    Molekulargewicht

    23718 Da

    Gen-ID

    3569

    NCBI Accession

    NP_000591

    Pathways

    TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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