TLR9 Antikörper (AA 26-300)
Kurzübersicht für TLR9 Antikörper (AA 26-300) (ABIN951280)
Target
Alle TLR9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 26-300
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Spezifität
- This antibody detects Toll-like Receptor 9 (TLR9).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Bovine (84 %), Cat (85 %), Dogs (83 %), Pig (84 %), Monkey (95 %).
Species reactivity (tested):Human. -
Aufreinigung
- Immunoaffinity Chromatography.
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Immunogen
- Recombinant protein fragment containing a sequence corresponding to a region within amino acids 26 and 300 of Human CD289(TLR9).
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.71 mg/mL
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Buffer
- 0.1 M Tris-glycine, pH 7, 10 % Glycerol and 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- TLR9 (Toll-Like Receptor 9 (TLR9))
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Andere Bezeichnung
- CD289 / TLR9
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Hintergrund
- TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.Synonyms: Toll-like receptor 9, UNQ5798/PRO19605
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Gen-ID
- 54106
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NCBI Accession
- NP_059138
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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