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CD11b Antikörper (N-Term)

ITGAM Reaktivität: Human FACS, WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN951175
  • Target Alle CD11b (ITGAM) Antikörper anzeigen
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Bindungsspezifität
    • 16
    • 14
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 256-286, N-Term
    Reaktivität
    • 278
    • 179
    • 70
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Human
    Wirt
    • 155
    • 114
    • 103
    • 4
    • 1
    • 1
    Kaninchen
    Klonalität
    • 279
    • 95
    • 1
    Polyklonal
    Konjugat
    • 124
    • 37
    • 32
    • 28
    • 21
    • 11
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD11b Antikörper ist unkonjugiert
    Applikation
    • 279
    • 86
    • 79
    • 78
    • 63
    • 44
    • 38
    • 27
    • 23
    • 20
    • 13
    • 13
    • 12
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to CD11b.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 256-286 amino acids from the N-terminal region of human CD11b
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Andere Bezeichnung
    CD11b (ITGAM Produkte)
    Hintergrund
    CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
    Molekulargewicht
    127179 Da
    Gen-ID
    3684
    NCBI Accession
    NP_000623
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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