RASGRF1 Antikörper (Middle Region)

Produktnummer ABIN928864

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RASGRF1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RASGRF1 Antikörper (Middle Region) (ABIN928864)

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RASGRF1 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: RASGRF1 antibody was raised in rabbit using the middle region of RASGRF1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

RASGRF1 Blocking Peptide, (ABIN5615766), is also available for use as a blocking control in assays to test for specificity of this RASGRF1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RASGRF1

Target: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Andere Bezeichnung: RASGRF1

Hintergrund: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Synonyms: Polyclonal RASGRF1 antibody, Anti-RASGRF1 antibody, Ras protein-specific guanine nucleotide-releasing factor 1 antibody, CDC25 antibody, CDC25L antibody, GNRP antibody, GRF1 antibody, GRF55 antibody, H-GRF55 antibody, PP13187 antibody.

Pathways: RTK Signalweg, Zellzyklus, M Phase