Cullin 2 Antikörper (Middle Region)
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- Target Alle Cullin 2 (CUL2) Antikörper anzeigen
- Cullin 2 (CUL2)
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Xenopus laevis
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cullin 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus, Ratte (Rattus), Hund, Rind (Kuh), Frosch
- Aufreinigung
- Purified
- Immunogen
- CUL2 antibody was raised in rabbit using the middle region of CUL2 as the immunogen
- Top Product
- Discover our top product CUL2 Primärantikörper
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- Applikationshinweise
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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CUL2 Blocking Peptide, catalog no. 33R-3799, is also available for use as a blocking control in assays to test for specificity of this CUL2 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- Cullin 2 (CUL2)
- Andere Bezeichnung
- CUL2 (CUL2 Produkte)
- Synonyme
- cul2 antikoerper, Cullin-2 antikoerper, fj48a06 antikoerper, wu:fj48a06 antikoerper, cullin-2 antikoerper, LOC100221330 antikoerper, 1300003D18Rik antikoerper, 4932411N15Rik antikoerper, AI327301 antikoerper, mKIAA4106 antikoerper, ATCUL2 antikoerper, F22D16.2 antikoerper, F22D16_2 antikoerper, cullin 2 antikoerper, cullin 2 antikoerper, cullin-2 antikoerper, putative cullin-2 (cul-2) antikoerper, cullin 2 L homeolog antikoerper, Cullin-2 antikoerper, cul2 antikoerper, CUL2 antikoerper, PTRG_05231 antikoerper, Smp_079740 antikoerper, LOC100550749 antikoerper, Cul2 antikoerper, cul2.L antikoerper, cul-2 antikoerper
- Hintergrund
- CUL2 is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. This protein may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). Synonyms: Polyclonal CUL2 antibody, Anti-CUL2 antibody, cullin 2 antibody, MGC131970 antibody.
- Pathways
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom
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