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Cullin 2 Antikörper (AA 591-742)

CUL2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7148749
  • Target Alle Cullin 2 (CUL2) Antikörper anzeigen
    Cullin 2 (CUL2)
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 591-742
    Reaktivität
    • 74
    • 39
    • 25
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 70
    • 3
    • 1
    Kaninchen
    Klonalität
    • 63
    • 11
    Polyklonal
    Konjugat
    • 32
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cullin 2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 29
    • 14
    • 13
    • 12
    • 12
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Cullin-2 protein (591-742AA)
    Isotyp
    IgG
    Top Product
    Discover our top product CUL2 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Cullin 2 (CUL2)
    Andere Bezeichnung
    CUL2 (CUL2 Produkte)
    Synonyme
    cul2 antikoerper, Cullin-2 antikoerper, fj48a06 antikoerper, wu:fj48a06 antikoerper, cullin-2 antikoerper, LOC100221330 antikoerper, 1300003D18Rik antikoerper, 4932411N15Rik antikoerper, AI327301 antikoerper, mKIAA4106 antikoerper, ATCUL2 antikoerper, F22D16.2 antikoerper, F22D16_2 antikoerper, cullin 2 antikoerper, cullin 2 antikoerper, cullin-2 antikoerper, putative cullin-2 (cul-2) antikoerper, cullin 2 L homeolog antikoerper, Cullin-2 antikoerper, cul2 antikoerper, CUL2 antikoerper, PTRG_05231 antikoerper, Smp_079740 antikoerper, LOC100550749 antikoerper, Cul2 antikoerper, cul2.L antikoerper, cul-2 antikoerper
    Hintergrund

    Background: Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).

    Aliases: Cul2 antibody, CUL 2 antibody, CUL-2 antibody, CUL2 antibody, CUL2_HUMAN antibody, cullin 2 antibody, cullin homolog 2 antibody, Cullin-2 antibody, MGC131970 antibody

    UniProt
    Q13617
    Pathways
    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom
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