TRADD Antikörper (Middle Region)

Produktnummer ABIN926870

Der Kaninchen Polyklonal Anti-TRADD Antikörper wurde für WB validiert. Er ist geeignet, TRADD in Proben von Human und Hund zu detektieren.

Kurzübersicht für TRADD Antikörper (Middle Region) (ABIN926870)

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRADD Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität: Hund

Aufreinigung: Purified

Immunogen: TRADD antibody was raised in rabbit using the middle region of TRADD as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TRADD Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TRADD antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Andere Bezeichnung: TRADD

Hintergrund: TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. Synonyms: Polyclonal TRADD antibody, Anti-TRADD antibody, TNFRSF1A-associated via death domain antibody, Hs.89862 antibody, MGC11078 antibody.

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C