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TRADD Antikörper (AA 1-312)

TRADD Reaktivität: Human WB, IHC, ELISA, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7173904
  • Target Alle TRADD Antikörper anzeigen
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-312
    Reaktivität
    • 47
    • 18
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 46
    • 4
    Kaninchen
    Klonalität
    • 46
    • 4
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRADD Antikörper ist unkonjugiert
    Applikation
    • 39
    • 26
    • 26
    • 19
    • 14
    • 10
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Andere Bezeichnung
    TRADD (TRADD Produkte)
    Synonyme
    TRADD antikoerper, Hs.89862 antikoerper, 9130005N23Rik antikoerper, AA930854 antikoerper, wu:fc59e02 antikoerper, zgc:103556 antikoerper, tradd antikoerper, TNFRSF1A associated via death domain antikoerper, conjugal transfer protein D antikoerper, TNFRSF1A-associated via death domain antikoerper, TNFRSF1A-associated via death domain L homeolog antikoerper, tnfrsf1a-associated via death domain antikoerper, TRADD antikoerper, traDd antikoerper, Tradd antikoerper, tradd.L antikoerper, tradd antikoerper
    Hintergrund

    Background: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

    Aliases: 9130005N23Rik antibody, AA930854 antibody, TNFR1 associated DEATH domain protein antibody, TNFR1-associated DEATH domain protein antibody, TNFRSF1A associated via death domain antibody, TNFRSF1A-associated via death domain antibody, tradd antibody, TRADD_HUMAN antibody, Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody, Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody

    UniProt
    Q15628
    Pathways
    NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C
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