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TRADD Antikörper (AA 111-230)

TRADD Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN673314
  • Target Alle TRADD Antikörper anzeigen
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-230
    Reaktivität
    • 47
    • 17
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 4
    Kaninchen
    Klonalität
    • 46
    • 4
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRADD Antikörper ist unkonjugiert
    Applikation
    • 39
    • 27
    • 26
    • 20
    • 14
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse of mouse TRADD
    Isotyp
    IgG
    Top Product
    Discover our top product TRADD Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Chen, Zhang, Zhang, Li, Sun: "Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling." in: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1304-9, (2016) (PubMed).

  • Target
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    Andere Bezeichnung
    TRADD (TRADD Produkte)
    Synonyme
    TRADD antikoerper, Hs.89862 antikoerper, 9130005N23Rik antikoerper, AA930854 antikoerper, wu:fc59e02 antikoerper, zgc:103556 antikoerper, tradd antikoerper, TNFRSF1A associated via death domain antikoerper, conjugal transfer protein D antikoerper, TNFRSF1A-associated via death domain antikoerper, TNFRSF1A-associated via death domain L homeolog antikoerper, tnfrsf1a-associated via death domain antikoerper, TRADD antikoerper, traDd antikoerper, Tradd antikoerper, tradd.L antikoerper, tradd antikoerper
    Hintergrund

    Synonyms: AA930854, 9130005N23Rik, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tradd

    Background: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.

    Gen-ID
    71609
    UniProt
    Q3U0V2
    Pathways
    NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C
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