CDC42 Antikörper (N-Term)

Produktnummer ABIN926862

Der Kaninchen Polyklonal anti-CDC42 Antikörper (ABIN926862) detektiert spezifisch CDC42 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund und Huhn.

Kurzübersicht für CDC42 Antikörper (N-Term) (ABIN926862)

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Reaktivität: Human, Maus, Ratte, Hund, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDC42 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Huhn, Hund

Aufreinigung: Purified

Immunogen: CDC42 antibody was raised in rabbit using the N terminal of CDC42 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CDC42 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CDC42 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CDC42

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Andere Bezeichnung: CDC42

Hintergrund: CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Synonyms: Polyclonal CDC42 antibody, Anti-CDC42 antibody, cell division cycle 42, GTP binding protein, 25kDa antibody, CDC42Hs antibody, G25K antibody.

Pathways: MAPK Signalweg, Microtubule Dynamics, RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling