AIF Antikörper (N-Term)

Produktnummer ABIN926855

Der Kaninchen Polyklonal Anti-AIF-Antikörper wurde für WB und IHC validiert. Er ist geeignet, AIF in Proben von Human, Rind (Kuh) und Hund zu detektieren.

Kurzübersicht für AIF Antikörper (N-Term) (ABIN926855)

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Reaktivität: Human, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-AIF Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Rind (Kuh), Hund

Aufreinigung: Purified

Immunogen: PDCD8 antibody was raised in rabbit using the N terminal of PDCD8 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PDCD8 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this PDCD8 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu AIF

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Andere Bezeichnung: PDCD8

Hintergrund: AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Synonyms: Polyclonal PDCD8 antibody, Anti-PDCD8 antibodyRP3-438D16.2 antibody, AIF antibody, MGC111425 antibody.

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effekt