AKR1C1 Antikörper (N-Term)

Produktnummer ABIN926427

Dieses Anti-AKR1C1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AKR1C1 in WB. Geeignet für Human.

Kurzübersicht für AKR1C1 Antikörper (N-Term) (ABIN926427)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKR1C1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: AKR1 C1 antibody was raised in rabbit using the N terminal of AKR1 1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

AKR1C1 Blocking Peptide, (ABIN940312), is also available for use as a blocking control in assays to test for specificity of this AKR1C1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: AKR1C1

Hintergrund: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Synonyms: Polyclonal AKR1C1 antibody, Anti-AKR1C1 antibody, aldo-keto reductase family 1, member C1, dihydrodiol dehydrogenase 1, 20-alpha, 3-alpha-hydroxysteroid dehydrogenase antibody, 2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, MBAB antibody, MGC8954 antibody.

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process