XPC Antikörper (AA 395-445)

Produktnummer ABIN8125779

Der Kaninchen Polyklonal anti-XPC Antikörper wird verwendet zum Nachweis von XPC in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für XPC Antikörper (AA 395-445) (ABIN8125779)

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-XPC Antikörper

Bindungsspezifität: AA 395-445

Verwendungszweck: XPC Antibody

Spezifität: This antibody detects endogenous levels of XPC at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human XPC AA range: 395-445

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu XPC

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Andere Bezeichnung: XPC

Hintergrund:

Background: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009],

Gene Name: XPC XPCC

Protein Name: XPC

Gen-ID: 7508

UniProt: Q01831

Pathways: p53 Signalweg, DNA Reparatur