ULK1 Antikörper (pSer757)

Produktnummer ABIN8125603

Der Kaninchen Monoklonal anti-ULK1 Antikörper (Klon AB2194) (ABIN8125603) detektiert spezifisch ULK1 in WB, ELISA, IF und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ULK1 Antikörper (pSer757) (ABIN8125603)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ULK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB2194

Produktdetails anti-ULK1 Antikörper

Bindungsspezifität: pSer757

Verwendungszweck: ULK1 (Phospho Ser757) Rabbit mAb

Spezifität: The antibody detects endogenous levels of ULK1 protein only when phosphorylated at Ser757. The antibody does not cross-react with ULK1 phosphorylated at other sites.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Andere Bezeichnung: ULK1

Hintergrund:

Synonyms: ULK1, KIAA0722, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, ATG1, hATG1, Unc-51-like kinase 1

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein. , function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells. , similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. , similarity:Contains 1 protein kinase domain. , subunit:Interacts with GABARAP and GABARAPL2. , tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung. ,

Gene Name: ULK1

Protein Name: ULK1 (Phospho Ser757)

Gen-ID: 8408

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagie