JAK2 Antikörper (pTyr1008)

Produktnummer ABIN8122379

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JAK2 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für JAK2 Antikörper (pTyr1008) (ABIN8122379)

Target: JAK2 (Janus Kinase 2 (JAK2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-JAK2 Antikörper

Bindungsspezifität: pTyr1008

Verwendungszweck: Jak2 (Phospho Tyr1008) Antibody

Spezifität: This antibody detects endogenous levels of Human Mouse Jak2 (phospho-Tyr1008)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Jak2 (Tyr1008)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu JAK2

Target: JAK2 (Janus Kinase 2 (JAK2))

Andere Bezeichnung: Jak2

Hintergrund:

Synonyms: Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)

Background: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],

Gene Name: JAK2

Protein Name: Jak2 (Tyr1008)

Gen-ID: 3717

UniProt: O60674

Pathways: JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response