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AIM2 Antikörper (AA 255-354)

AIM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN760766
  • Target Alle AIM2 Antikörper anzeigen
    AIM2 (Absent in Melanoma 2 (AIM2))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 255-354
    Reaktivität
    • 68
    • 23
    • 17
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 55
    • 12
    • 2
    Kaninchen
    Klonalität
    • 60
    • 9
    Polyklonal
    Konjugat
    • 38
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIM2 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 33
    • 32
    • 22
    • 13
    • 12
    • 12
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse AIM2
    Isotyp
    IgG
    Top Product
    Discover our top product AIM2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AIM2 (Absent in Melanoma 2 (AIM2))
    Andere Bezeichnung
    Aim2 (AIM2 Produkte)
    Synonyme
    AIM2 antikoerper, PYHIN4 antikoerper, Gm1313 antikoerper, Ifi210 antikoerper, absent in melanoma 2 antikoerper, AIM2 antikoerper, Aim2 antikoerper
    Hintergrund

    Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2

    Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.

    Gen-ID
    383619
    UniProt
    Q91VJ1
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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