AIM2 Antikörper

Produktnummer ABIN1882191

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-AIM2 Antikörper (Klon 812CT9-2-2-1) (ABIN1882191) detektiert spezifisch AIM2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AIM2 Antikörper (ABIN1882191)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 812CT9-2-2-1

Produktdetails anti-AIM2 Antikörper

Aufreinigung: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This AIM2 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 10-40 region of human AIM2.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-AIM2 Antikörper (ABIN1882191)

Chen, Ou-Yang, Hung, Liu, Wang, Wang, Hou, Hortobagyi, Hung: "AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model." in: Molecular cancer therapeutics, Vol. 5, Issue 1, pp. 1-7, (2006) (PubMed).

Cresswell, Clarke, Jackson, Darcy, Trapani, Johnstone: "Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2." in: Biochemical and biophysical research communications, Vol. 326, Issue 2, pp. 417-24, (2004) (PubMed).

DeYoung, Ray, Su, Anzick, Johnstone, Trapani, Meltzer, Trent: "Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma." in: Oncogene, Vol. 15, Issue 4, pp. 453-7, (1997) (PubMed).

Details zu AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Andere Bezeichnung: AIM2

Hintergrund: Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

Molekulargewicht: 38954

NCBI Accession: NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome