NRF2 Antikörper (N-Term)

Produktnummer ABIN8106688

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NRF2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NRF2 Antikörper (N-Term) (ABIN8106688)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NRF2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NFE2L2 Antibody - N-terminal region

Sequenz: DILWRQDIDL GVSREVFDFS QRRKEYELEK QKKLEKERQE QLQKEQEKAF

Homologie: Cow: 86%, Dog: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 92%, Rat: 93%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2L2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38744-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung: NFE2L2

Hintergrund:

Background Information: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Gene Name: nuclear factor, erythroid 2 like 2

Alternative Symbols: NRF2, HEBP1, Nrf-2, IMDDHH

Protein Name: nuclear factor erythroid 2-related factor 2

Molekulargewicht: 66 kDa

Gen-ID: 4780

NCBI Accession: NP_006155

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling